HONG KONG SCIENCE PARK PHASE 3 • HARDWARE PROFILE

Analytical Fleet & Instrumentation

World-class chromatography, high-resolution mass spectrometry, and trace elemental hardware operated under strict ISO/IEC 17025 metrological calibration.

1300 bar
UHPLC Pressure Limit
Agilent 1290 Infinity II
240,000
Orbitrap Resolution (FWHM)
Thermo Exploris HRMS
< 1.0 ppb
Elemental Sensitivity
Agilent 7900 ICP-MS
0.1 µg
Micro-Balance Precision
Mettler Toledo XPR6

Engineered for Uncompromising Metrological Precision

Analytical precision is fundamentally bounded by the physical environment in which instruments operate. Headquartered at Hong Kong Science Park Phase 3, our laboratory clean suites are custom-engineered from the ground up to eliminate acoustic vibration, thermal drift, and airborne contamination.

Our chromatographic suites maintain continuous positive-pressure HEPA filtration (ISO Class 7 cleanrooms) with dedicated climate controllers maintaining temperatures at 20.0°C ± 0.5°C and relative humidity at 45% ± 5% RH 24 hours a day, 365 days a year. All high-resolution mass spectrometers are mounted upon pneumatic Sorbothane vibration-isolation optical platforms to prevent acoustic or structural interference with Orbitrap ion orbital frequencies.

Core Analytical Instrumentation Platforms

Explore the specifications and analytical roles of our primary instrumentation fleet.

PRIMARY CHROMATOGRAPHY

Agilent 1290 Infinity II UHPLC System

Agilent Technologies • Waldbronn, Germany

The Agilent 1290 Infinity II represents the pinnacle of liquid chromatography. Equipped with high-pressure binary pumps delivering up to 1300 bar operating pressure, active damping, and sub-2-micron core-shell column chemistry (ZORBAX Eclipse Plus C18 / C8). Dual-wavelength Diode Array Detectors (DAD) monitor absorption continuously across 190 nm to 400 nm.

Max Pressure: 1300 bar (18,850 psi)
Flow Range: 0.05 – 5.0 mL/min
Detector: Max-Light DAD (60mm flow cell)
Autosampler: Multi-sampler @ 4°C cooled
EXACT MASS & STRUCTURE

Thermo Scientific Orbitrap Exploris HRMS

Thermo Fisher Scientific • Bremen, Germany

High-Resolution Accurate-Mass (HRAM) mass spectrometer providing exact monoisotopic molecular weight confirmation, multivalent charge envelope deconvolution, and amino acid sequence identification. Heated Electrospray Ionization (H-ESI II) delivers gentle ionization with sub-ppm mass accuracy.

Resolution: Up to 240,000 FWHM @ m/z 200
Mass Accuracy: < 1 ppm internal lock-mass
Mass Range: m/z 40 – 6,000
Ion Source: Heated ESI (Pos/Neg polarity)
TANDEM MASS SPECTROMETRY

Sciex Triple Quad 6500+ LC-MS/MS

AB Sciex • Framingham, MA, USA

Ultra-sensitive triple quadrupole mass spectrometer with IonDrive technology for targeted Multiple Reaction Monitoring (MRM). Delivers unmatched signal-to-noise for ultra-trace impurity quantitation and synthesis byproduct profiling down to femtogram levels.

Scan Speed: Up to 12,000 Da/sec
Polarity Switching: 5 msec fast switching
Dynamic Range: Up to 6 orders of magnitude
Quantitation: MRM / Scheduled MRM
TRACE ELEMENTAL IMPURITIES

Agilent 7900 ICP-MS Quadrupole Spectrometer

Agilent Technologies • Tokyo, Japan

Inductively Coupled Plasma Mass Spectrometry equipped with Ultra High Matrix Introduction (UHMI) and 4th-generation Octopole Reaction System ($ORS^4$) helium collision cell to eliminate polyatomic interferences for parts-per-billion heavy metal screening.

Plasma Temp: ~10,000 K Argon plasma
Sensitivity: > 1,000 M cps/ppm @ low matrix
Collision Cell: He / H₂ / O₂ reactive gases
Limits: < 0.1 ppb for Pb, Cd, Hg, As

Daily Metrological Calibration & Maintenance Protocols

To ensure every published Certificate of Analysis represents absolute empirical precision, all instruments undergo systematic daily calibration prior to batch sample injection:

Daily NIST Alignment

Wavelength verification with Holmium Oxide UV filters; MS mass scale tuning with Pierce FlexMix calibration solutions.

System Suitability Standard

USP system suitability reference injections verifying chromatographic peak symmetry ($T \le 1.5$) and retention reproducibility.

Traceable Audit Logs

Instrument run logs, pressure traces, and raw sequence files are archived for 10 years under ISO 27001 data governance.

Put Our Analytical Fleet to Work

Benefit from pharmaceutical-grade analytical instrumentation with guaranteed turnaround and double-blind testing integrity.

CERTIFIED • BV
ISO/IEC 27001
Bureau Veritas UKAS
HOKLAS ACCREDITED
HKAS Lab #0842
Chemical & Testing Lab
HOKLAS / ISO
ISO 15189:2022
Medical Diagnostic Lab
INTERNATIONAL
ISO/IEC 17025
ILAC-MRA Competence